Hemophagocytic Lymphohistiocytosis

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Hemophagocytic Lymphohistiocytosis

Hemophagocytic lymphohistiocytosis (HLH) is a condition in which the body makes too many activated immune cells (macrophages and lymphocytes).

People with HLH usually develop symptoms within the first months or years of life.

It occurs when there is an uncontrollable proliferation of hyper-activated macrophages and T-lymphocytes. The hyper-activated macrophages engulf haematopoietic cells resulting in a deregulated immune system, which in turn attacks various tissues in the body. The weakened body becomes susceptible to infection. Main symptoms and co-morbidities for HLH include:

Autoimmune conditions
Leukaemia
Lymphomas
HSCT
Infection (especially with EBV)
Diabetes
Obesity
COPD
Heart Failure

Epidemiology Data

Data Available: Incidence Data

Data covers: Males and Females (where applicable) from 2010 to 2050.

Data is split into 5 year age ranges (0-4, 5-9 etc) from 0 to 100+ years, across multiple countries.

Additional sub filters of the data are available. Please see the below pop up box for more information.

Once purchased, the data will be provided in an embedded PowerBI document, in which the data can be filtered and viewed in a way which suits your needs. Raw data can also be downloaded. Below is an example embedded data set which can be filtered in a similar way.

Instructions:
Once the data set has been purchased, please refresh this page. The example data set will then be replaced with actual data.

Please contact us for further information regarding filtering of the data, viewing the data, data available, custom quotes, or anything else.

As well as incidence, data can be filtered by the following attributes :

• Classification Primary HLH
• Classification Secondary HLH

Further sub sets are available within the data. Please contact us for more information.

Austria
Belgium
Brazil
Canada
China
Denmark
Finland
France
Germany
India
Ireland
Italy
Japan
Netherlands
Norway
Russian Federation
Spain
Sweden
Switzerland
United Kingdom
United States of America

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